You can use global Black Lists on your StreamRail account that will impact all your Ad Sources per environment.
By clicking on Restrictions under Settings, you’ll be taken to a page which will let you configure these Black Lists by environment.
Just select a list in one or more of the environments, decide if you’d like to also block subdomains from this list, and when clicking “save” on the bottom of the page, the selected list will take effect over all Ad Sources (from the selected environment) in your account.
Please take into consideration that this will affect not only Ad Sources that already exist, but also new Ad Sources that will be created in the future.